We explored how zinc lozenges affect the duration of the common cold through a detailed analysis of multiple trials. In particular, we focused on the Mossad (1996) trial involving zinc gluconate lozenges, which revealed an average reduction of cold duration by about 4.0 days. While that sounds promising, our findings through a quantile treatment effect (QTE) analysis tell a more nuanced story.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
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8
Vitamin C reduces cold severity
Vitamin C reduces the severity of common colds: a meta-analysis.
We explored how vitamin C affects the severity of common colds through a comprehensive review of available studies. By including only randomized, placebo-controlled trials where participants received at least 1 gram of vitamin C daily, we aimed to investigate both the overall duration of colds and the intensity of symptoms experienced.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
Read More
8
Vitamin C's potential benefits highlighted
Bias against Vitamin C in Mainstream Medicine: Examples from Trials of Vitamin C for Infections.
We assessed the longstanding debate about vitamin C’s effectiveness in treating the common cold. This exploration reveals that evidence has consistently indicated that vitamin C can indeed help reduce the duration and severity of cold symptoms in certain circumstances.
However, despite this evidence, mainstream medicine has often favored what we call eminence-based medicine, relying on influential figures rather than empirical data. The skepticism surrounding vitamin C largely traces back to three pivotal studies published in 1975, two in JAMA and one in the American Journal of Medicine. These studies have shaped the narrative in textbooks and nutritional guidelines, despite exhibiting notable flaws that we carefully examined.
Furthermore, we highlighted misleading reporting in recent randomized trials and critical editorials published in JAMA regarding vitamin C. While our critique largely focuses on this journal, it reflects a broader trend across medical literature, indicating a possible bias against acknowledging the benefits of vitamin C in fighting colds.
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Most Useful Reviews
9
Prevents common colds
1 people found this helpful
Tastes pleasant, prevents colds effectively, and boosts immunity during flu season.
Read More
9
Family favourite
1 people found this helpful
A constant purchase; it belongs in every first-aid kit. At the first sign of a cold, it works remarkably well—trusted by the entire family!
Read More
9
Quick recovery
1 people found this helpful
Excellent! After a cold, I took this for five consecutive days. I genuinely feel better; I highly recommend it as a household essential!
We explored the potential benefits of vitamin C as a supplementary treatment for relieving common cold symptoms. By analyzing data from 10 randomized controlled trials, all focused on patients in China, we sought to understand how combining vitamin C with antiviral therapy might enhance recovery.
Our findings revealed that vitamin C supplementation could significantly improve overall efficacy, with a reported relative risk of 1.27. Moreover, it was shown to shorten the time it takes for symptoms to get better and for patients to heal, compared to antiviral therapy alone.
While vitamin C seems to have a positive impact when paired with antiviral drugs, it’s essential to note that its individual effects might not be fully clear due to the combined treatment approach used in the studies. Nonetheless, vitamin C presents itself as a promising addition to traditional cold treatments, helping patients manage their symptoms more effectively.
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9
Zinc's potential in virus treatment
Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions.
We explored the effectiveness of zinc in combination with herbal polyphenols against respiratory RNA viruses, including the common cold. In this study, the researchers combined zinc picolinate with various flavonoids to see if it could reduce viral replication and load without harming healthy cells.
The results were quite promising, showing a significant reduction of 50-95% in the genome replication levels of viruses like the human coronavirus OC43, influenza A virus, and human metapneumovirus. This suggests that zinc, when paired with appropriate compounds, may play a beneficial role in treating infections that lead to the common cold.
However, it's important to note that while the study shows a notable decrease in viral activity, it did not specifically isolate the effects of zinc alone. Thus, we cannot definitively state that zinc by itself is effective against the common cold without considering the contributions of the other substances involved.
Overall, this research opens the door for developing a potential treatment that is not toxic and sourced from natural ingredients, which could be effective against various RNA viruses with the hope of remaining effective even amidst mutating strains.
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9
Zinc shortens cold duration variability
Quantile Treatment Effect of Zinc Lozenges on Common Cold Duration: A Novel Approach to Analyze the Effect of Treatment on Illness Duration.
We explored how zinc lozenges affect the duration of the common cold through a detailed analysis of multiple trials. In particular, we focused on the Mossad (1996) trial involving zinc gluconate lozenges, which revealed an average reduction of cold duration by about 4.0 days. While that sounds promising, our findings through a quantile treatment effect (QTE) analysis tell a more nuanced story.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
Read More
9
Elderberry effectively reduces cold symptoms
Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials.
We explored the effects of black elderberry (Sambucus nigra) on upper respiratory symptoms, particularly in the context of common colds and flu. This analysis included 180 participants and looked at various factors, including vaccination status and the nature of the symptoms experienced.
Our findings indicated that elderberry supplementation was effective in significantly reducing upper respiratory symptoms. The results showed a substantial average effect, suggesting that this natural remedy could provide an alternative to the overuse of antibiotics and prescription medications for viral infections.
With concerns about safety and efficacy of traditional treatments, elderberry presents a promising option for those seeking relief from cold and flu symptoms without relying on conventional drugs.
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9
Elderberry may reduce cold symptoms
Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial.
This study implemented a randomized, double-blind, placebo-controlled design to explore whether elderberry supplements could improve respiratory health for air travelers. We observed 312 economy class passengers traveling from Australia to an overseas destination, aiming to see if a standardized elderberry extract could lessen the duration and severity of cold episodes.
Participants recorded their cold symptoms in daily diaries and completed surveys measuring their upper respiratory conditions and overall quality of life at various points before and after travel. While both groups experienced cold episodes, it was notable that those taking the placebo had a longer duration of symptoms and reported feeling worse overall. Specifically, the placebo group faced cold symptoms for an average of 117 days, compared to just 57 days for those receiving elderberry, and their average symptom scores were substantially higher.
Our analysis points to the potential benefits of elderberry in reducing both the duration and severity of cold symptoms for people traveling by air. However, additional research is necessary to confirm these findings and delve deeper into the possible effects of elderberry on both physical and mental health.
The common cold is a viral infection of the upper respiratory tract, primarily affecting the nose and throat. It's caused by a variety of viruses, with rhinoviruses being the most prevalent. Symptoms generally include a runny or stuffy nose, sore throat, cough, sneezing, mild headache, and sometimes a low-grade fever. While the common cold is often mild and resolves on its own within a week or two, it can still be bothersome and impact daily activities.
Transmission occurs through respiratory droplets when an infected person coughs or sneezes, or by touching surfaces contaminated with the virus. Preventative measures include frequent handwashing, using hand sanitizer, and avoiding close contact with infected individuals. Since there is currently no cure for the common cold, treatment focuses on symptom relief through over-the-counter medications, adequate rest, and hydration. While colds may be uncomfortable, they are generally not serious; however, seeking medical attention may be necessary if symptoms worsen or persist for an extended period.
Elderberry (Sambucus) refers to a genus of flowering plants in the family Adoxaceae, comprising several species known for their small berries and traditional medicinal uses. The most commonly recognized species is the European elder, Sambucus nigra, which has been utilized in folk medicine for centuries due to its rich nutrient profile, including antioxidants, vitamins A and C, and dietary fiber. Elderberries are typically fragrant clusters of small, dark purple to black berries that are used in a variety of culinary applications, such as jams, syrups, and wine.
In recent years, elderberry has gained popularity for its potential health benefits, particularly for supporting immune health. Many people consume elderberry supplements or syrups to help alleviate symptoms of colds and flu, with some studies suggesting they may reduce the duration and severity of viral infections. However, it’s important to note that raw elderberries, as well as other parts of the elderberry plant, can be toxic if consumed in large amounts. Therefore, it's recommended to use elderberry products that are properly processed and prepared to ensure safety and efficacy.
While elderberry, particularly from the Sambucus species, has gained popularity as a natural remedy for the common cold, research into its effectiveness is still ongoing. Some studies suggest that elderberry extract may help reduce the duration and severity of cold and flu symptoms. The berries are rich in antioxidants and vitamins, which can support the immune system and may aid in fighting off viral infections. Many people take elderberry syrup or capsules at the onset of cold symptoms, and anecdotal evidence supports its use in reducing congestion and providing relief from other cold-related discomforts.
However, it's important to note that while elderberry may provide some benefits, it should not be regarded as a cure for the common cold. The best approach is to use elderberry as a complementary treatment alongside other remedies, such as rest, hydration, and over-the-counter medications, as needed. Always consult with a healthcare professional before starting any new supplement, especially for individuals with underlying health conditions or those who are pregnant or nursing.
Based on user reviews, users typically report seeing results at the first sign of a common cold. Many reviewers emphasize the importance of taking the supplement early, with one user mentioning it works remarkably well "at the first sign of a cold" Read Review. Another user notes they have successfully managed to "nip it in the bud" by taking the product at the onset of symptoms Read Review.
The timeframe to experience relief seems to fluctuate among individuals but is generally reported within a few days of starting the supplement. One user stated they felt better after taking the product for five consecutive days Read Review. In summary, for optimal results, many users advocate beginning use at the first signs of a cold, with benefits often felt within a short period after consistent use.
Vitamin C has garnered attention in the context of managing common cold symptoms, with scientific research revealing promising insights into its efficacy. Studies have shown that while vitamin C does not generally prevent colds, regular supplementation of 1 g or more daily can reduce the severity of symptoms by approximately 15% and may shorten their duration, particularly for those under physical stress [1]. For individuals experiencing severe symptoms, vitamin C appears even more beneficial, potentially alleviating discomfort during the early stages of illness [2]. This highlights its role as a viable option for symptom management during a cold.
Interestingly, a rigorous study on South Korean soldiers found that a daily dose of 6,000 mg of vitamin C led to a 20% lower incidence of colds, particularly among recruits subjected to physical stress [7]. While these findings underscore vitamin C's potential, it is essential to note that no substantial evidence exists indicating its effectiveness against COVID-19. Overall, the safety, affordability, and supportive evidence for vitamin C in reducing cold severity make it a recommended consideration for those looking to manage their symptoms more effectively.
According to user reviews, many individuals report notable improvements in their symptoms when using the product at the first signs of a cold. For instance, one user emphasizes its effectiveness by stating it is a "constant purchase" that belongs in every first-aid kit, working remarkably well "at the first sign of a cold" Read Review. Others echo similar sentiments, indicating that they experienced significant relief when utilizing the product early on; one user specifically noted that the lozenges “work wonders” at the onset of symptoms Read Review.
Additionally, some reviews highlight the overall enhancement in immune support during cold and flu season. Users have reported that the product not only helps in alleviating cold symptoms but also plays a vital role in boosting immunity. For example, a user described the supplement as a "saviour" packed with essential ingredients like zinc and elderberry, which effectively support immunity during colds Read Review. These anecdotal experiences suggest that many have found success in preventing or mitigating colds when using the product proactively, although individual results can vary.
Based on user reviews, many individuals report successfully combining this supplement with other immune-boosting ingredients, particularly zinc, elderberry, and vitamin C. Users frequently mention the synergistic effects of these components, emphasizing how they may enhance each other's efficacy in supporting the immune system during cold season. One user highlights the combination of zinc and elderberry, stating it effectively supports immunity during colds Read Review. Another review notes that the blend of these ingredients works excellently at the first sign of a common cold, suggesting that users find the supplement more effective when paired with these essential nutrients Read Review.
Moreover, several reviewers assert that taking the supplement at the onset of symptoms has allowed them to proactively manage cold symptoms or even prevent them altogether. One user recalls how a family member trusts the product for early intervention at the first signs of a cold Read Review. Others echo these sentiments, with specific anecdotes about keeping illness at bay through diligent use alongside other supportive supplements Read Review. These collective experiences indicate that users find value in using this product in conjunction with other vitamin and mineral supplements for optimal immune function during the cold season.
Elderberry, particularly in the form of standardized extracts, has shown promise in alleviating symptoms of the common cold. Research indicates that elderberry supplementation may help reduce the duration and severity of symptoms when taken soon after the onset of illness. One study highlighted that participants taking elderberry experienced about a 50% improvement in symptoms such as fever, headache, and nasal congestion within just a few days of treatment [13]. Additionally, another trial focused on air travelers suggested that those using elderberry supplements reported a significantly shorter duration of cold symptoms, averaging 57 days of symptoms compared to 117 days in the placebo group [15].
While these results are encouraging, it is important to approach them with a sense of caution. The overall body of evidence for elderberry's efficacy in treating the common cold remains somewhat mixed, as comprehensive research is limited [16]. Therefore, while some individuals may find relief with elderberry, more thorough studies are necessary to clearly establish the optimal dosage and to understand its full potential in cold symptom management. Until more conclusive data is available, elderberry might be worth considering as a complementary option alongside traditional remedies for those seeking to manage cold symptoms more effectively.
9
Family favourite
1 people found this helpful
A constant purchase; it belongs in every first-aid kit. At the first sign of a cold, it works remarkably well—trusted by the entire family!
7.5
Effective prevention
1 people found this helpful
These elderberry tablets taste like sweet berry candy. I let them dissolve on my tongue and take one every half hour at the first sign of a cold or sore throat. So far, I’ve managed to prevent getting sick; they seem to nip it in the bud.
9
Quick recovery
1 people found this helpful
Excellent! After a cold, I took this for five consecutive days. I genuinely feel better; I highly recommend it as a household essential!
9
Delicious help
Excellent composition! These delicious lollipops work wonders at the first sign of a common cold, helping greatly.
9
Essential cold remedy
Great product! All the essentials in one jar. At the first sign of a common cold, our saviour.
6
Supports immunity
This synergistic complex with zinc, elderberry, and vitamin C effectively supports immunity during colds.
6
A tremendous aid
2 people found this helpful
Fight the cold! This fantastic blend of zinc, elderberry, and vitamin C is perfect for use at the earliest signs of a common cold. I find it helpful every other day!
We investigated how vitamin C affects the common cold, focusing on its potential for prevention and treatment. Research indicates that while vitamin C does not prevent colds in the general population when taken at doses over 1 g/day, it has been beneficial for individuals engaging in heavy physical activity, effectively halving their incidence of colds.
Looking into regular supplementation, we found that taking 1 g or more daily can reduce the severity of colds by about 15%. However, when it comes to starting vitamin C after cold symptoms begin, results are less consistent, though higher doses of 6-8 g/day did significantly shorten the duration of colds compared to lower doses.
Interestingly, historical studies showed that vitamin C might prevent pneumonia in specific populations, such as schoolboys or soldiers, but this doesn’t translate to the general public. While some trials indicated potential benefits for pneumonia patients, the evidence is not conclusive.
Overall, we see that given the evidence supporting reduced severity and duration of colds, along with its safety and affordability, it may be worth considering a higher dose of vitamin C for those looking to manage cold symptoms better.
8
Vitamin C reduces cold severity
Vitamin C reduces the severity of common colds: a meta-analysis.
We explored how vitamin C affects the severity of common colds through a comprehensive review of available studies. By including only randomized, placebo-controlled trials where participants received at least 1 gram of vitamin C daily, we aimed to investigate both the overall duration of colds and the intensity of symptoms experienced.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
8
Vitamin C reduces cold incidence
Vitamin C supplementation reduces the odds of developing a common cold in Republic of Korea Army recruits: randomised controlled trial.
We conducted an insightful study to explore whether vitamin C supplementation can help reduce the incidence of common colds among Republic of Korea Army recruits. Our research involved a rigorous randomised, placebo-controlled trial that included 1,444 soldiers over a 30-day period.
In this study, we divided the participants into two groups: one received a daily dose of 6,000 mg of vitamin C while the other received a placebo with no vitamin C. We investigated the soldiers' medical records to see how many of them contracted a cold during the training period.
Our findings showed encouraging results. The group that took vitamin C had a 20% lower risk of developing a common cold compared to those who took the placebo. Interestingly, this protective effect was especially pronounced among recruits in certain training camps, as well as never smokers and those who were physically ranked at level three.
Overall, we observed that vitamin C supplementation appears to be an effective strategy for reducing the incidence of common colds in military settings, which may lead to considerations for implementing vitamin C provisions during basic training for soldiers.
8
Elderberry may ease cold symptoms
The effects of berry on acute respiratory viral infections: A rapid review of clinical studies.
We examined the potential benefits of elderberry in reducing symptoms associated with acute respiratory viral infections, particularly the common cold and influenza. Our review looked at five clinical studies involving 936 adults, focusing on the effects of elderberry when taken within 48 hours of the onset of symptoms.
The findings suggest that elderberry, particularly in mono-herbal preparations such as extracts or lozenges, may help alleviate various symptoms. Participants reported a notable reduction in fever, headache, nasal congestion, and mucus discharge within just a few days of treatment—averaging a remarkable 50% improvement.
However, we found that the evidence regarding elderberry's effectiveness for symptoms like cough and the need for additional medications remains unclear and inconsistent. Overall, while the results are promising, there's no evidence to support elderberry's use for preventing or treating COVID-19 specifically. Adverse effects were generally rare, occurring more commonly with placebo treatments, and there's insufficient information regarding safety during pregnancy or lactation.
9
Elderberry may reduce cold symptoms
Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial.
This study implemented a randomized, double-blind, placebo-controlled design to explore whether elderberry supplements could improve respiratory health for air travelers. We observed 312 economy class passengers traveling from Australia to an overseas destination, aiming to see if a standardized elderberry extract could lessen the duration and severity of cold episodes.
Participants recorded their cold symptoms in daily diaries and completed surveys measuring their upper respiratory conditions and overall quality of life at various points before and after travel. While both groups experienced cold episodes, it was notable that those taking the placebo had a longer duration of symptoms and reported feeling worse overall. Specifically, the placebo group faced cold symptoms for an average of 117 days, compared to just 57 days for those receiving elderberry, and their average symptom scores were substantially higher.
Our analysis points to the potential benefits of elderberry in reducing both the duration and severity of cold symptoms for people traveling by air. However, additional research is necessary to confirm these findings and delve deeper into the possible effects of elderberry on both physical and mental health.
8
Elderberry shows mixed effectiveness
Respiratory and allergic diseases: from upper respiratory tract infections to asthma.
We explored the potential benefits of elderberry in treating the common cold. Research indicates that elderberry may shorten the duration of symptoms, offering some hope for those suffering from this pesky illness. However, it is important to note that while there was one encouraging study regarding elderberry's use for flu, the overall evidence supporting its effectiveness for the common cold isn't robust and lacks extensive research details.
This leaves us with a mixed outlook on elderberry's capabilities. More thorough and repeat studies are necessary to establish clear benefits to ensure a solid understanding of how well it works for common cold symptoms. It’s clear that elderberry shows promise, but we need more compelling data to feel confident in recommending it as a go-to remedy for colds.
References
Hemilä H, Chalker E. Vitamin C for the common cold and pneumonia. Pol Arch Intern Med. 2025;135. doi:10.20452/pamw.16926
Hemilä H, Chalker E. Vitamin C reduces the severity of common colds: a meta-analysis. BMC Public Health. 2023;23:2468. doi:10.1186/s12889-023-17229-8
Hemilä H, Chalker E. Bias against Vitamin C in Mainstream Medicine: Examples from Trials of Vitamin C for Infections. Life (Basel). 2022;12. doi:10.3390/life12010062
Murni IK, Prawirohartono EP, Triasih R. Potential Role of Vitamins and Zinc on Acute Respiratory Infections Including Covid-19. Glob Pediatr Health. 2021;8:2333794X211021739. doi:10.1177/2333794X211021739
Ran L, Zhao W, Wang H, Zhao Y, Bu H. Vitamin C as a Supplementary Therapy in Relieving Symptoms of the Common Cold: A Meta-Analysis of 10 Randomized Controlled Trials. Biomed Res Int. 2020;2020:8573742. doi:10.1155/2020/8573742
Schloss J, Lauche R, Harnett J, Hannan N, Brown D, et al. Efficacy and safety of vitamin C in the management of acute respiratory infection and disease: A rapid review. Adv Integr Med. 2020;7:187. doi:10.1016/j.aimed.2020.07.008
Kim TK, Lim HR, Byun JS. Vitamin C supplementation reduces the odds of developing a common cold in Republic of Korea Army recruits: randomised controlled trial. BMJ Mil Health. 2022;168:117. doi:10.1136/bmjmilitary-2019-001384
Nault D, Machingo TA, Shipper AG, Antiporta DA, Hamel C, et al. Zinc for prevention and treatment of the common cold. Cochrane Database Syst Rev. 2024;5:CD014914. doi:10.1002/14651858.CD014914.pub2
Kreiser T, Zaguri D, Sachdeva S, Zamostiano R, Mograbi J, et al. Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions. Pharmaceuticals (Basel). 2022;15. doi:10.3390/ph15030377
Hemilä H, Chalker E, Tukiainen J. Quantile Treatment Effect of Zinc Lozenges on Common Cold Duration: A Novel Approach to Analyze the Effect of Treatment on Illness Duration. Front Pharmacol. 2022;13:817522. doi:10.3389/fphar.2022.817522
Wang MX, Win SS, Pang J. Zinc Supplementation Reduces Common Cold Duration among Healthy Adults: A Systematic Review of Randomized Controlled Trials with Micronutrients Supplementation. Am J Trop Med Hyg. 2020;103:86. doi:10.4269/ajtmh.19-0718
DeGeorge KC, Ring DJ, Dalrymple SN. Treatment of the Common Cold. Am Fam Physician. 2019;100:281.
Harnett J, Oakes K, Carè J, Leach M, Brown D, et al. The effects of berry on acute respiratory viral infections: A rapid review of clinical studies. Adv Integr Med. 2020;7:240. doi:10.1016/j.aimed.2020.08.001
Hawkins J, Baker C, Cherry L, Dunne E. Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complement Ther Med. 2019;42:361. doi:10.1016/j.ctim.2018.12.004
Tiralongo E, Wee SS, Lea RA. Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2016;8:182. doi:10.3390/nu8040182
Jaber R. Respiratory and allergic diseases: from upper respiratory tract infections to asthma. Prim Care. 2002;29:231.